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Molecular mechanism of extreme mechanostability in a pathogen adhesin

Science Magazine / Milles, L. F., Schulten, K., Gaub, H. E., Bernardi, R. C. - - Reading time < 1 mins - Share :
High resilience to mechanical stress is key when pathogens adhere to their target and initiate infection. Using atomic force microscopy–based single-molecule force spectroscopy, we explored the mechanical stability of the prototypical staphylococcal adhesin SdrG, which targets a short peptide f...

Erythrocytic ferroportin reduces intracellular iron accumulation, hemolysis, and malaria risk

Science Magazine / Zhang, D.-L., Wu, J., Shah, B. N., Greutelaers, K. C., Ghosh, M. C., Ollivierre, H., Su, X.-z., Thuma, P. E., Bedu-Addo, G., Mockenhaupt, F. P., Gordeuk, V. R., Rouault, T. A. - - Reading time < 1 mins - Share :
Malaria parasites invade red blood cells (RBCs), consume copious amounts of hemoglobin, and severely disrupt iron regulation in humans. Anemia often accompanies malaria disease; however, iron supplementation therapy inexplicably exacerbates malarial infections. Here we found that the iron exporte...

Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell-driven tumor immunity

Science Magazine / Ferrari de Andrade, L., Tay, R. E., Pan, D., Luoma, A. M., Ito, Y., Badrinath, S., Tsoucas, D., Franz, B., May, K. F., Harvey, C. J., Kobold, S., Pyrdol, J. W., Yoon, C., Yuan, G.-C., Hodi, F. S., Dra - - Reading time < 1 mins - Share :
Ads from Inoreader • Remove MICA and MICB are expressed by many human cancers as a result of cellular stress, an...

Mobile apps could hold key to Parkinson's research, care

Medical Xpress - - Reading time 2 mins - Share :
A new study out today in the journal JAMA Neurology shows that smartphone software and technology can accurately track the severity of the symptoms of Parkinson's disease. The findings could provide researchers and clinicians with a new tool to both develop new drugs and better treat this challen...
More from Futurity
Futurity / Mark Michaud-Rochester - Smartphone app tracks Parkinson’s symptoms

Newly-discovered human organ may help explain how cancer spreads

New Scientist - - Reading time 2 mins - Share :
A newly discovered network of fluid-filled channels in the human body may be a previously-unknown organ, and it seems to help move cancer cells around the body
More from Medical Xpress, Live Science
Live Science - Meet Your 'Interstitium,' A Newfound Organ
Medical Xpress - Newfound 'organ' had been missed by standard method for visualizing anatomy

Rats can’t puke, which is bad news for them and great news for us

Popular Science / Erin Blakemore - - Reading time 4 mins - Share :
Ads from Inoreader • Remove Animals We could use their unique talents to develop better chemo d...

Honeybees may unlock the secrets of how the human brain works

Medical Xpress - - Reading time 3 mins - Share :
Ads from Inoreader • Remove Researchers from the University of Sheffield have discovered that looking at honeybe...

Prep for fetal surgery involves kickball, chicken breasts

Futurity / Marin Hedin-Johns Hopkins - - Reading time 3 mins - Share :
To rehearse for complex surgery on the spinal cords of fetuses, surgeons are practicing on kickballs and chicken breasts. These items, combined with high-tech 3D printing technology, are providing surgical teams with the practice they need to perform a complex but minimally invasive new surgical...

Neuroscientists say daily ibuprofen can prevent Alzheimer's disease

Medical Xpress - - Reading time 3 mins - Share :
A Vancouver-based research team led by Canada's most cited neuroscientist, Dr. Patrick McGeer, has successfully carried out studies suggesting that, if started early enough, a daily regimen of the non-prescription NSAID (nonsteroidal anti-inflammatory drug) ibuprofen can prevent the onset of Alzh...
More from ScienceDaily
ScienceDaily - Neuroscientists say daily ibuprofen can prevent Alzheimer's disease

Infants as young as 17 months expect fairness and equity

Medical Xpress - - Reading time 2 mins - Share :
Children as young as 17 months recognise whether resources are being shared fairly, the first time researchers have found evidence that infants so young are sensitive to principles of "distributive justice".

Scientists develop new tool to study nicotine receptors

Medical Xpress - - Reading time 2 mins - Share :
Ads from Inoreader • Remove A team of scientists has developed a new technique to better understand the effects ...

Drug-resistant gene goes from pig farms to patients worldwide

Medical Xpress - - Reading time 3 mins - Share :
A troublesome gene that is resistant to an antibiotic often used as a last resort has been tracked from its origins on Chinese pig farms to hospital patients worldwide in a new study led by UCL and Peking University People's Hospital.

Street drug laced with BUG SPRAY transforms casual users into crazed ZOMBIES

Naturalnews.com / Tracey Watson - - Reading time 2 mins - Share :
(Natural News) One of the least expensive but deadliest street drugs available today is known as KD, Katie or Zombie. This drug may contain different ingredients, but the common denominator is always bug spray. Users take marijuana, banana leaves, tobacco or spice and lace it with a bug spray, mo...
More from Live Science
Live Science - Are People Actually Smoking Bug-Spray-Laced Drugs? Either Way, It's a Bad Idea.

Use of most-prescribed diabetes drug, metformin, during pregnancy found to increase risk of obesity in the child

Naturalnews.com / Zoey Sky - - Reading time 2 mins - Share :
(Natural News) According to the results of a study, women who take metformin, a common diabetes medication, could be putting their children at increased risk of being obese or overweight. More pregnant women with gestational diabetes or polycystic ovary syndrome (PCOS) are taking metformin to t...
More from ScienceDaily
ScienceDaily - New study elucidates link between PCOS and anxiety

Treating triple negative breast cancer by targeting pair of receptors

Medical Xpress - - Reading time 2 mins - Share :
Ads from Inoreader • Remove Triple negative breast cancer (TNBC) is a particularly aggressive form of breast can...

For Women With Low-Risk Pregnancies, Technology Can Reduce Doctor Visits

NPR / Michelle Andrews - - Reading time 4 mins - Share :
Ads from Inoreader • Remove In a program called OB Nest, The Mayo Clinic has been using a telemedicine program t...

Ian Paterson: Disgraced surgeon's patients at 'heart' of inquiry

BBC - - Reading time 1 mins - Share :
Ads from Inoreader • Remove More than 150 patients have contributed to the inquiry into Ian Paterson's botched o...

Image of the Day: Hungry Hookworms

The Scientist - - Reading time < 1 mins - Share :
Researchers discover anti-malarials called quinolones can halt the development of the parasites, offering a potential therapeutic avenue.
More from ScienceDaily, Medical Xpress
Medical Xpress - Scientists identify potential drug target in blood-feeding hookworms
ScienceDaily - Scientists identify potential drug target in blood-feeding hookworms

Caloric Restriction Slows Signs of Aging in Humans

The Scientist - - Reading time 1 mins - Share :
Findings from a randomized, controlled trial finds that reducing food intake decreases metabolism and reduces oxidative damage to tissues and cells.
More from ScienceDaily, New Scientist, Medical Xpress, Live Science
Live Science - Could Cutting Calories Slow Down Aging?
Medical Xpress - Calorie restriction trial in humans suggests benefits for age-related disease
New Scientist - Calorie restriction may extend lifespan by changing your sleep
ScienceDaily - Calorie restriction trial in humans suggests benefits for age-related disease

300 million hepatitis B sufferers but only one in 20 treated: study

Medical Xpress - - Reading time 1 mins - Share :
Some 300 million people worldwide are living with the deadly hepatitis B virus (HBV), but only one in 20 received adequate treatment, researchers reported Tuesday.

S.Africa's DIY battle against HIV

Medical Xpress - - Reading time 3 mins - Share :
Ads from Inoreader • Remove Self-testing kits and vending machines distributing prescription drugs are two ways ...